Dr. Iosof Vaisman, Department of Bioinformatics and Computational Biology, George Mason University
The main focus of his research is on the development of novel algorithms and tools for protein structure and function analysis and study of structure-function relationships in proteins.
Selected research projects:
Development of new metrics for protein similarity comparisons based on topological descriptors derived from the Delaunay tessellation.
Development of new method for protein structure alignment based on topological substructure descriptors.
Development of novel methods for the analysis of structure-function correlations in proteins using computational mutagenesis.
Development of the domain assignment methods in multidomain protein structures based on the properties of Delaunay networks.
Development of scoring functions for evaluation of protein-ligand interactions for the transmembrane pore proteins (in collaboration with Dr. Vladimir Karginov).